Is it time to expand the use of cardiac resynchronization therapy to patients with mildly symptomatic heart failure?
نویسنده
چکیده
منابع مشابه
Cardiac resynchronization therapy for mild heart failure.
It has been firmly established that cardiac resynchronization therapy (CRT) reduces symptoms and improves mortality in patients with moderate-to-severe chronic heart failure [New York Heart Association (NYHA) class III-IV], despite optimal heart failure medication and with wide QRS complex on the surface electrocardiogram as evidence of ventricular dyssynchrony, but not whether such treatment i...
متن کاملCritical appraisal of the use of cardiac resynchronization therapy beyond current guidelines.
Cardiac resynchronization therapy (CRT) is an effective treatment for patients with drug-refractory, chronic heart failure. Multiple single-center and multicenter studies have shown significant reductions in left ventricular (LV) volumes and an increase in LV systolic function. More importantly, CRT reduces mortality and morbidity during long-term follow-up. Current guidelines consider CRT as a...
متن کاملBrain natriuretic peptide and cardiac resynchronization therapy in patients with mildly symptomatic heart failure.
BACKGROUND There are limited data on the prognostic implications of brain natriuretic peptide (BNP) assessment in patients with mildly symptomatic heart failure (HF) who receive cardiac resynchronization therapy with a defibrillator (CRT-D). METHODS AND RESULTS The effect of elevated baseline and 1-year BNP levels (dichotomized at the upper tertile BNP of 120 pg/mL) on the risk of HF or death...
متن کاملHeart Failure Effect of Cardiac Resynchronization Therapy on Reverse Remodeling and Relation to Outcome Multicenter Automatic Defibrillator Implantation Trial: Cardiac Resynchronization Therapy
Background—Cardiac resynchronization therapy (CRT) plus implantation of an implantable cardioverter defibrillator (ICD) reduced the risk of death or heart failure event in patients with mildly symptomatic heart failure, left ventricular dysfunction, and wide QRS complex compared with an ICD only. We assessed echocardiographic changes in patients enrolled in the MADIT-CRT trial (Multicenter Auto...
متن کاملCardiac resynchronization therapy. Indications and contraindications.
Progress in medical therapy wouldn't be possible without the contribution of the scientific community. Several randomized controlled trials have led to our current guidelines. Specifically, COMPANION and CARE-HF trials involved a turning point for cardiac resynchronization therapy, which became well recognized for the treatment of heart failure patients with QRS≥120ms, ejection fraction≤35%, an...
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عنوان ژورنال:
- Journal of the American College of Cardiology
دوره 54 20 شماره
صفحات -
تاریخ انتشار 2009